Have you seen the above before? Your screw hole is stripped and a there's a crack on either side of the hole?
When it's cracked, it's cracked and we do recommend fixing the crack first before using your Screw-it-Again anchor. While in 98% of the cases the anchor will perform as designed in some instances the crack could get bigger as the anchor expands to create a tight grip. Depending on the nature of the crack it could be damaging to the cabinet, door frame or other repair you are working on. So when there's a crack, fix the crack first!